Semantic representation of Gene Ontology terms by using Gene Regulation Ontology
نویسندگان
چکیده
Gene Ontology (GO) has been developed to provide concepts for the functional annotation of biological entities. This development has already contributed to significant biomedical research results. Nonetheless, GO could have provided even stronger support to biomedical text mining, if it delivered domain-independent logical definitions of its concepts. We present a method that extracts the semantic structures of GO terms by using the Gene Regulation Ontology (GRO). The method annotates substrings of GO terms with, if any, corresponding concepts of OBO ontologies and then converts the syntactic structures of GO terms into GRO-based semantic structures. We show that the semantic structures can be used to deduce implied relations from GO terms.
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